Critical review of clinical trial data on acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI). [2015]

Evidence-based guidelines collection from the American Thoracic Society (ATS).

Evidence-based consensus guidelines, from German working group on analgesia, sedation and delirium management in intensive care. [2010]

Tools for promoting the principles of evidence-based decision making in intensive care, with recommendations), links, and a selective journal club.

Evidence-based guidelines on intensive care medicine, available as downloadable PDFs. From the European Society of Intensive Care Medicine (ESICM).

Highlights some of the paradigm shifts seen in processes of critical care, including the limitations of randomized trials. [2015]

Reviews the benefits of parenteral nutrition (PN) in critically ill patients, and the best clinical trial evidence in support. [2015]

Critical examination of some of the most recent randomized trials performed in Intensive Care, analyzing their premises, hypothesis and outcome. [2015]

Critically reviews and assesses the effect of RRTs on reducing cardiopulmonary arrest and hospital mortality rates. [2010]

Although the ability to reproduce experiments is a defining principle of evidence-based science, this scoping review found that a minority of published critical care practices were evaluated for reproducibility, and less than half had reproducible effects.