Choroideremia (CHM) is an X-linked recessive eye disease causing degeneration of the choriocapillaris, retinal pigment epithelium, and photoreceptors, leading to severe visual impairment by adulthood. The pathogenetic mechanisms are unknown. The first clinical manifestation in CHM is night blindness during early adulthood followed by reduction of central vision and constriction of visual fields. The choroid and retina undergo complete atrophy. Heterozygous female carriers have no visual defect but often show striking funduscopic changes such as irregular pigmentation and atrophy around the optic disc.
A hereditary disorder that leads to abnormality of retinal receptors and severe visual impairment at an early age, often from birth. LCA is an autosomal recessive disease. There is no cure, but new advancements in gene therapy may prove promising in the not-too-distant future.
Macular Degeneration is a condition that mainly affects those over 60 years old (age related) but can also affect children and teenagers (juvenile). The condition affects the eyes Macula, in some cases causing it to stop working entirely which causes blindness.
Please submit only websites relating to ARMD (Age Related Macular Degeneration) or Juvenile Macular Degeneration. Organizations should be submitted to the sub-category "Organizations". Websites selling products should be submitted to the "shopping" subcategory.
Retinitis Pigmentosa is a hereditary eye condition affecting the retina. Patients suffer from a form of "tunnel vision" and night blindness most commonly. This category includes both informational sites and organizations.
Please submit only sites that relate to Retinitis Pigmentosa. Other retinal eye disorders can be found in the top level Eye_Disorders category.
Retinoschisis is an X-linked recessive eye disease leading to moderate to severe visual handicap at late adulthood. Affected males usually have mild visual impairment during childhood, often discovered at routine visus controls at schools. Some patients may stay symptomless till adulthood. Most patients retain reasonable vision until fifth or sixth decades when some deterioration usually takes place. Total blindness is an exception.